Prof. Kazem  Karami |  AI in Drug Discovery |  Best Researcher Award

academic-member of chemistry department at  isfahan university of technology , Iran.

Prof. Dr. Kazem Karami, born on March 30, 1966, in Ilam, Iran, is a distinguished Iranian chemist renowned for his extensive contributions to the field of inorganic and organometallic chemistry. He currently serves as a Professor in the Department of Chemistry at Isfahan University of Technology, where he has been shaping the future of chemical science through teaching, mentorship, and cutting-edge research since 2006.

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🎓 Academic Background:

Dr. Karami holds a Ph.D. in Inorganic Chemistry from Bu-Ali Sina University, where he conducted advanced research under the supervision of Prof. S.J. Sabounchei. His dissertation focused on the synthesis and characterization of keto-stabilized phosphorus ylides and various metal complexes, a theme that would define much of his future work. Prior to this, he earned his M.Sc. from Tehran University of Teacher Training and a B.Sc. from Lorestan University.

🔬 Research Interests:

Prof. Karami’s research encompasses a broad and impactful range of topics, including:

• Design and synthesis of bioactive organometallic complexes

• C-H activation and cyclopalladation involving phosphorus ylides

• Development of orthopalladated complexes for anticancer applications

• Nanocomposites for environmental remediation and biosensing

• Advanced studies in coordination chemistry, sol-gel processes, and catalysis

His work has consistently bridged synthetic chemistry with biological and environmental relevance, particularly through interactions of complexes with DNA, BSA, and cancer cell lines.

🏆 Awards & Scientific Leadership:

With a career marked by research excellence and leadership, Prof. Karami has been involved in more than 15 research projects funded by the Iranian National Science Foundation (INSF). Many of his projects focus on anticancer metal complexes, environmental chemistry, and nanostructured materials. He has also served on editorial boards and national research committees, reflecting his status as a thought leader in his field.

Publication:

1. In Vitro Cytotoxicity Studies of Palladacyclic Complexes Containing the Symmetric Diphosphine Bridging Ligand: Studies of Their Interactions With DNA and BSA

2. Design and Synthesis of a Novel Trinuclear Palladium(II) Complex Containing an Oxime Chelate Ligand: Determining the Interaction Mechanism With the DNA Groove and BSA Site I

3. Palladium Nanoparticles Supported on Polymer: An Efficient and Reusable Heterogeneous Catalyst for the Suzuki Cross-Coupling Reactions and Aerobic Oxidation of Alcohols

4. BSA Nanoparticles as Controlled Release Carriers for Isophthalaldoxime Palladacycle Complex: Synthesis, Characterization, In Vitro Evaluation, Cytotoxicity, and Release

5. Application of Dimeric Orthopalladate Complex of Homoveratrylamine as an Efficient Catalyst in the Heck Cross-Coupling Reaction

6. Synthesis and Application of Ortho-Palladated Complex of (4-Phenylbenzoylmethylene) Triphenylphosphorane as a Highly Active Catalyst in the Suzuki Cross-Coupling Reaction

7. A Novel TMD/MOF Composite for Highly Selective Adsorption of Methylene Blue Dye From Aqueous Mixture of MB and MO

8. A Novel Nanohybrid Based on MIL-101(Cr)/PANI/Ag for the Adsorption of Cationic Methylene Blue Dye From Aqueous Solution

9. Synthesis and Characterization of Two New Trans Palladium(II) Complexes Containing Benzylamine Ligand: DNA/BSA Interactions, Molecular Docking, and In Vitro Cytotoxic Activity

10. An Efficient Palladium Catalytic System for Microwave-Assisted Cyanation of Aryl Halides

11. Synthesis of a Novel Trinuclear Palladium Complex: The Influence of an Oxime Chelate Ligand on Biological Evaluation Toward Double-Strand DNA, BSA Protein, and Molecular Docking

12. Bis(Dibenzylidene Acetone) Palladium(0) Catalyst for Glycerol Oxidation in Half Cell and in Alkaline Direct Glycerol Fuel Cell

13. Synthesis and Spectroscopic Characterization Study of New Palladium Complexes Containing Bioactive O,O-Chelated Ligands: Evaluation of the DNA/Protein BSA Interaction and In Vitro Cytotoxicity

14. Dinuclear Bridged Biphosphinic and Mononuclear Cyclopalladated Complexes of Benzylamines: Synthesis, Structural Characterization, and Antitumor Activity

15. Application of Dimeric Orthopalladated Complex in Suzuki–Miyaura Cross-Coupling Reaction Under Microwave Irradiation and Conventional Heating

16. An Investigation on MIL-101(Fe)/PANI/Pd Nanohybrid as a Novel Photocatalyst Based on MIL-101(Fe) MOF for Removing Methylene Blue Dye

17. Cyclopalladated Complexes of 2-Phenylaniline and Their Catalytic Activity in Suzuki and Heck Reactions Under Mild Conditions

18. Synthesis, Characterization, and Molecular Docking of New C,N-Palladacycles Containing Pyridinium-Derived Ligands: DNA and BSA Interaction Studies

19. Polyethylene Glycol-Supported Recyclable NC Palladacycle Catalyst for Heck Cross-Coupling Reactions

20. Synthesis, Spectroscopic Characterization, and In Vitro Cytotoxicities of New Organometallic Palladium Complexes With Biologically Active β-Diketones: Biological Evaluation and Docking Studies