Dr. Huai-Jen Tsai is a distinguished molecular biologist whose influential work spans molecular biology, marine biotechnology, developmental biology, and gene transgenesis in aquatic organisms. Renowned for pioneering advancements in plasmid gene transfer, he has significantly shaped the understanding of microbial genetics and its applications in biotechnology. His early research on gene conjugation between lactic acid bacteria laid foundational insights for modern microbial engineering. He is widely recognized for his contributions to fish molecular biology, particularly in growth hormone gene evolution, pathogen characterization, and genomic techniques for aquatic species. Dr. Tsai’s innovative work in transgenesis has advanced the development of genetically enhanced aquatic models, including the notable golden zebrafish technology that earned major scientific accolades. His studies in marine pathogens have strengthened global approaches to aquatic disease diagnostics and prevention. Through extensive publications in leading journals, he has elevated the scientific understanding of aquatic genomics and marine microbial interactions. His leadership within major academic and research institutions has fostered interdisciplinary growth, driving progress in biotechnology and life sciences. Over the years, he has been celebrated for groundbreaking inventions, high-impact research, and excellence in teaching and mentorship. His achievements continue to influence fields ranging from aquaculture biotechnology to developmental genetics. Dr. Tsai remains a respected global figure whose contributions have shaped both fundamental science and applied innovations in marine and molecular biology.
Publications
Extracellular Pgk1 interacts neural membrane protein enolase-2 to improve the neurite outgrowth of motor neurons. (2023). Communications Biology.
The promising role of a zebrafish model employed in neural regeneration following a spinal cord injury. (2023). [Journal name unavailable].
Genomic structure, protein character, phylogenic implication, and embryonic expression pattern of a zebrafish new member of zinc finger BED-type gene family. (2023). Genes.
Anp32a promotes neuronal regeneration after spinal cord injury of zebrafish embryos. (2022). International Journal of Molecular Sciences.
Quantification of Idua enzymatic activity combined with observation of phenotypic change in zebrafish embryos provide a preliminary assessment of mutated idua correlated with mucopolysaccharidosis type I. (2022). Journal of Personalized Medicine.