Dr. Roland Bruderer | Computational Proteomics | Outstanding Scientist Award

Published on by Computational Biologists

Dr. Roland Bruderer | Computational Proteomics | Outstanding Scientist Award 

Biognosys AG | Switzerland 

Roland Bruderer is a leading proteomics researcher specializing in mass spectrometry–based analytical technologies and advanced LC-MS workflows for large-scale protein analysis. His research focuses on the development of robust, high-throughput proteomics platforms that enable deep and reproducible profiling of complex biological samples. He has made seminal contributions to data-independent acquisition strategies, particularly SWATH mass spectrometry, significantly expanding the depth and consistency of whole-proteome measurements. His work has demonstrated the feasibility of identifying and quantifying more than ten thousand proteins in single analytical runs, setting new standards for proteome coverage. In addition, he has contributed to quality control and bioinformatics solutions for immunopeptidomics and large-scale proteomics datasets. His research addresses protein interactions, post-translational modifications, and metabolite–protein interactions using innovative mass spectrometry approaches. By integrating analytical chemistry with molecular and cell biology, his work supports applications in systems biology, translational research, and precision medicine. He is recognized for translating complex methodological innovations into scalable, industry-ready proteomics workflows.

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Dr. Karolina Stępień | Extracellular Matrix | Best Researcher Award 

Published on by Computational Biologists

Dr. Karolina Stępień | Extracellular Matrix | Best Researcher Award 

Medical University of Silesia | Poland

Dr. Karolina Stępień is a molecular biologist and medical scientist specializing in the extracellular matrix (ECM) and its role in connective tissue and vascular diseases, particularly abdominal aortic aneurysm (AAA). Her research explores the molecular architecture and remodeling of the ECM, focusing on collagens, elastin, metalloproteinases, and thrombospondins to understand vascular wall degeneration and identify biomarkers for prognosis and therapy. Beyond vascular pathology, she has contributed to studies on osteogenesis imperfecta and the potential of induced pluripotent stem cells (iPSCs) in gene therapy and regeneration, as well as on epithelial-mesenchymal transition (EMT) in pediatric craniopharyngioma as a predictor of tumor recurrence. Her work, published in leading journals such as International Journal of Molecular Sciences, Biomolecules, and Journal of Applied Genetics, advances knowledge of ECM-driven disease mechanisms and molecular medicine. As an educator at the Medical University of Silesia, she teaches molecular biology and genetics, integrating research and clinical application. Leading the “BIOMOLEK” Scientific Club, she mentors young researchers in ECM biology and molecular diagnostics. She actively participates in international scientific collaborations and conferences, strengthening the global exchange of knowledge in vascular and molecular pathology. Through her interdisciplinary research, teaching, and mentorship, Dr. Stępień continues to bridge fundamental molecular science with translational therapeutic innovation, shaping the future of biomedical research and education.