Assoc. Prof. Halil İbrahim Güler is a distinguished molecular biologist and geneticist whose research unites enzymology, proteomics, bioinformatics, and microbial genetics. A graduate of Sivas Cumhuriyet University and Karadeniz Technical University (KTÜ), where he also earned his Ph.D., Güler’s early studies on Thermus plasmids laid the foundation for his focus on microbial adaptation and enzyme mechanisms. Currently serving as Associate Professor in KTÜ’s Department of Molecular Biology and Genetics, he leads innovative research on microbial enzymes—particularly β-glucosidases—and designs biocatalysts for industrial and medical applications. Using structural modeling, molecular docking, and dynamics simulations, he explores enzyme-ligand interactions and develops compounds with antitumor, antidiabetic, and anti-Alzheimer potential. His prolific publications highlight contributions to biocatalyst design, protein stability, and natural product biosynthesis. As an educator and mentor, he teaches courses in Bioinformatics, Microbial Ecology, and Gene Manipulation, fostering data-driven and experimental proficiency among students. His administrative roles and participation in research committees reflect his dedication to institutional growth and scientific collaboration. Through his academic leadership and interdisciplinary research, Güler continues to advance molecular genetics and biotechnology in Turkey and beyond.